Hit optimization for ECF-T paper is out!

Starting the new year by publishing a paper Hit Optimization by Dynamic Combinatorial Chemistry on Streptococcus pneumoniae Energy-Coupling Factor Transporter (ECF)-PanT.

We had a great collaboration with the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), identifying potential hits for energy-coupling factor (ECF) transporters by computationally analyzing the binding pocket using molecular dynamics simulations.

Thanks to the great collaboration on this project — we’re looking forward to discovering more hits!